This is an OCR Gateway A level biology cheat sheet, Chapter 15 module 5. Specification reference: 5.1.1
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Maintenance of internal environment in constant state despite external changes.
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Fluctuations within normal range.
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Types of dynamic equilibrium:
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Negative feedback
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Works to reduce change (e.g. body temperature control)..
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Positive feedback
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Works to increase change (e.g. release of oxytocin in childbirth to increase frequency of contractions).
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Endotherms
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Rely on metabolic processes to provide heat.
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Ectotherms
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Rely on surroundings to provide heat.
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Ectotherms:
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Behavioural adaptations
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Move to shade / Sun, press bodies to heated surfaces.
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Physiological adaptations
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Change colour, alter heart rate.
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Endotherms:
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Cooling down
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Sweating, vasodilation, relaxed erector pili muscles.
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Heating up
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Vasoconstriction, raising hair/feathers, shivering.
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Carbohydrate metabolism
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Control blood glucose, amino acid
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Deamination
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Transamination - Conversion of amino acids into another
Deamination - Removal of amine groups from molecules because body cannot store amino acids and proteins (ornithine cycle). |
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Detoxification
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Hydrogen peroxide (+ catalase) --> O2 + H2O
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Liver cells = hepatocytes with adaptations such as large nuclei and golgi, lots of mitochondria.
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Blood from hepatic artery and portal vein mix in sinusoids to increase overall O2 content of blood.
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Happens in the glomerulus.
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Blood comes from vein into narrower afferent arteriole which creates high pressures, so blood goes through capillary walls.
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Arterioles surrounded by cells called podocytes with arm-like structures called pedicels.
These create slots to ensure molecules such as platelets that got through the epithelial and basement later do not enter the PCT (proximal convoluted tubule). |
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In the PCT.
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Glucose, amino acids, vitamins and hormones actively cotransported from filtrate back into blood.
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Adaptations:
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Microvili
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Mitochondria - ATP for active transport.
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In loop of Henle - descending limb
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Top = impermeable to water, lower part = permeable to water.
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Concentration of Na and Cl increases lower down the descending limb.
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Water therefore moves out into capillaries.
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Filtrate is very concentrated.
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- ascending limb
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Permeable to Na and Cl. Actively pumped out to medulla.
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Impermeable to water, so more dilute.
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Permeability varies with ADH.
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Na+ can also actively be pumped out.
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ADH (primary messenger) binds to receptors which trigger cAMP production.
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cAMP triggered realise of aquaporin-containing vesicles.
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Facilitates diffusion of water back into blood i.e. reabsorption of water.
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