Heparin Drug Info (exam 3)
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Heparin
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Blocks Prothrombin to Thrombin
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Prevents formation of clots
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Pulmonary embolism & thrombus
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Drug of Choice For:
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DIC
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Beef/Pork allergies or cultural/religious objections
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Thrombocytopenia
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Bleeding disorder
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Uncontrolled HTN: Heparin makes vessels more friable which could result in a fatal bleed
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Recent surgery
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GI ulcers
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Heparin induced thrombocytopenia with thrombosis (HITT)
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Thrombocytopenia
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Anticoagulants
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Penicillin
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Antihistamines
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Digoxin
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Nitroglycerin
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Nicotine
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Monitor Labs: CBC & PTT
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Assess for therapeutic drug effect & development of AE
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Antidote: Protamine Sulfate
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Administer in the event of Heparin overdose
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Administration Route:
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SubQ or IV
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Half-life
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90 min.
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Injection site may form Hematoma
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IV site will ooze and have more evident bruising
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PTT
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Therapeutic range = 45-70 sec.
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CBC
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Monitor for thrombocytopenia (<150)
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