Drug info for Enoxaparin
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Enoxaparin
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Blocks factors XA and IIA in clotting cascade
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DOC in hospitalized patients because it doesn't have massive systemic effects
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Spinal block/epidural: hematoma or bleeding may occur causing permanent neurological damage
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Anti-platelet drugs increase risk of thrombocytopenia
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Thrombocytopenia
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Toxicity (only if wrong dose is given)
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Neurological damage (r/t BBW)
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Route: SubQ
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Onset: 3-5 hours
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Half-life: 2-4 times longer than heparin
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Dosing: weight based --> predictable dose response
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No required lab monitoring d/t predictable dose response
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Instruct patient on self-administration
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Monitor for bleeding
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