Drug info for pioglitazone
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Pioglitazone
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Rosiglitazone
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Decrease insulin resistance
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Used to treat Type 2 Diabetes
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Active liver disease
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History of bladder cancer
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Severe heart failure
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Congestive Heart Failure
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Shortness of breath, Edema, Crackles/Rales
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Hepatotoxicity
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Cognitive Heart Failure
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Weight Gain
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Fluid Retention
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Will increase blood glucose levels
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Statins
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Will increase/decrease blood glucose levels
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Zoles, Rifampin, Cimetidine
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Monitor A1C and LFTs
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Monitor for signs & symptoms of CHF
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May take up to 12 weeks for max effects
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AST
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10-40
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ALT
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7-56
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A1C
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Goal: <6.5
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