Action, Indication, CI, C, AE, DI, & NI
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Blocks Vitamin K at sites of action
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Stroke/TIA
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A-fib
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DVT
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Blood disorders
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Hepatic Disease
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GI Ulceration
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MajoriBleeding
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Fetal Warfarin Syndrome (FWS)
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Developmental delays
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Low birth weight
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Poor growth
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Bleeding
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Increase effects of warfarin:
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Decrease Warfarin Effects:
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-NSAIDS
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-Birth Control
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-Bactrim
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-Spironolactone
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-PPIs
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-Haldol
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-H2 blockers
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|
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-Aprepitant
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Half-life = 24-72 hrs
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Remains in system 4-5 days
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PO at night at the same time
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Monitor Labs: CBC & PT/INR
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Administer antidote if OD occurs
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Vitamin K
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Educate pt. about diet
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Instruct patient to eat the same amount of foods containing vitamin K every week
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Emaciate Patients
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Not DOC because the decrease protein in blood increase risk of toxicity
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CBC
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no indication of thrombocytopenia
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PT
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18-30 seconds
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INR
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2-3
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