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Spherical Shaped
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Enveloped virus
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One lipid membrane
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Outer layer
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Corrugated due to protrusions
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Internal Core
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Dumbbell shaped
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Lateral bodies
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Two present in the concavities between outer layer and Core
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Outer core wall
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Palisade structure with T-shaped spike proteins
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Inner Core wall
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Smooth
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Attachment
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A17, A25, A26, A27, D8, H3
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Entry
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Entry Fusion Complex-A16, A21, A28, F9, G3, G9, H2, I2, J5, L1, L5, O3
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Redox active proteins
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E10, A2.5, and G4
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Phosphorylation
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Kinase- F10 & B1
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Dephosphorylation
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Phosphotase - H1
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Proteolytic processing
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proteinase - I7
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Bommana Chanakya
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Sushma Bhandarkar
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213501003
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213501004
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Bommana Chanakya
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Sushma Bhandarkar
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213501003
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213501004
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Terminal Regions
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Has ITRs with secondary hairpin loop structures that connect two DNA strands and contains the variable genes that are responsible for host cell interactions
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Central Regions
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Conserved genes responsible for replication and morphogenesis
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Attachment
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A17, A25, A26, A27, D8, H3
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Entry
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Entry Fusion Complex - A16, A21, A28, F9, G3, G9, H2, I2, J5, L1, L5, O3
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Redox active proteins
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E10, A2.5, and G4
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Phosphorylation
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Kinase - F10 and B1
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Dephosphorylation
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Phosphatase - H1
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Proteolytic processing
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Proteinase - I7
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Early Gene Proteins
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Inducing proliferation of neighbouring cells
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Counteracting host immune defences
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Some proteins can induce a second uncoating reaction thereby releasing the viral genome from the core
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Mediating replication of the genome
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Protiens In Replication
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Viral DNA polymerase
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Helicase-primase
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Uracil DNA glycosylase
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Single-stranded DNA-binding protein
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DNA ligase
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Holliday junction resolvase
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Proteins In Transcription
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RNA polymerase
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ETF
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Capping enzyme
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VITF-3
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VLTF-1, VLTF-2, VLTF-3, VLTF-4
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Release factor Elongation factor
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Poly(A) polymerase
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DNA topoisomerase
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Attachment
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Entry
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Early Gene Transcription
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DNA Replication
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Intermediate Gene Transcription
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Late Gene Transription
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Assembly
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Release
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