Treats type 2 diabetes mellitus
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Repaglinide
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Prandin
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Type 2 diabetes mellitus
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Hypoglycemia
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Nausea, Vomiting
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Monitor for signs of hypoglycemia (diaphoresis, tachycardia, fatigue, excessive hunger, tremors).
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If the client is conscious, give glucose orally in either pill form, glass of orange juice, 2–3 tsp of sugar, honey, or corn syrup dissolved in water.
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If the client is not conscious, give intravenous glucose; give parenteral glucagon if IV not available
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Check the client’s blood glucose every 15–20 minutes.
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Continue treatment until the blood glucose has returned to the expect- ed reference range and the client is no longer symptomatic.
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Monitor for persistent nausea, vomiting, or diarrhea.
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Monitor CBC levels
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Give orally 30 min or less before meals, usually three times a day
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Tell clients to skip a dose if they skip a meal and to add a dose if they add a meal.
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Do not exceed 4 doses a day.
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Wear a medical alert bracelet.
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Watch for and report symptoms of hypoglycemia.
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Test blood glucose to confirm.
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If hypoglycemia occurs, advise patient to take a glass of orange juice or 2–3 tsp of sugar, honey, or corn syrup dissolved in water (glucose, not table sugar, if taking miglitol), and notify health care professional.
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Retest in 15 to 20 min and repeat treatment if still low.
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Carry a carbohydrate snack at all times.
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Lie down when feeling nauseated.
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Consume adequate carbohydrates.
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Diabetic ketoacidosis
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Liver, kidney, and endocrine disorders
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Renal or hepatic dysfunction
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Systemic infection
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Older adults
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Use of alcohol, NSAIDs, warfarin, loop diuretics, and anabolic steroids
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Gemfibrozil (Lopid), erythromycin, and chloramphenicol increase hypo- glycemic effects.
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Alcohol, corticosteroids, and rifampin decrease hypoglycemic effects.
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