Fluroquinolones Cheat Sheet

A Education › Science cheat sheet in English by Drosario19

Used in the treatment of bacterial infections and UTIs. They also protect against anthrax after exposure to its spores.

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Floroq­uin­olones

Prototype Med
Ciprof­loxacin (Cipro)
Other Meds
Ofloxacin
 
Moxifl­oxacin (Avelox)
Used in the treatment of bacterial infections and UTIs. They also protect against anthrax after exposure to its spores.

Therap­eutic Use

Treats a wide range of bacterial infect­ions, including severe urinary tract disorders.
Prevents anthrax (following inhalation of anthrax spores) in both adults and children.

Adverse Drug Reactions

Dizziness, headache; confusion in older clients
nausea, vomiting, diarrhea
Achilles tendon rupture (rare), especially in older clients, and clients taking glucoc­ort­icoids, and transplant recipients
Photos­ens­itivity (sunbu­rn-like reaction) even with indirect sun exposure, sunlamp exposure; may occur despite use of sunscreen
Severe adverse reactions include seizures, intrac­ranial pressure, suicidal ideation, hepato­tox­icity, anaphy­laxis, CDAD

Nursing Interv­entions

Monitor for and report GI symptoms (a decrease in the dose may need to occur).
Monitor for and report tendon pain during treatment (disco­ntinue if pain occurs).
Don’t allow clients to go outdoors without covering their skin with clothing. They also need to apply sunscreen to areas of exposure.

Intera­ctions

Antacids, iron prepar­ations, calcium (including dairy products), and sucralfate (Carafate) decrease oral absorp­tion.
Increases theoph­ylline levels and the risk for CNS symptoms.
Increases warfarin (Coumadin) levels.
Concurrent use of erythr­omycin, quinidine, some antips­ych­otics, and tricyclic antide­pre­ssants can increase the risk for torsade de pointes in those suscep­tible.
Increased hypogl­ycemia may occur when taken concur­rently with antidi­abetic medica­tion.

Admini­str­ationdverse Drug Reacti­ons**

Available in oral and IV forms.
• Infuse slowly over at least 60 min; follow recomm­end­ations for dilution.
• Incomp­atible with multiple other drugs in IV solution or IV tubing.

Patient Education

Report CNS and GI symptoms to provider.
Decrease caffeine use during treatment.
Report tendon pain to provider.
Avoid exposure to sunlight or sunlam­p/wear sunscr­een­/pr­ote­ctive clothes
Take antacids, iron, calcium, dairy products, and sucralfate 2 hr after or 6 hr before oral ciprof­lox­acin.
Encourage patients to drink at least 1,500 to 2,000 mL of fluids/day

Contra­ind­ica­tions

Allergy to any fluoro­qui­nolone
Tendon pain
Myasthenia gravis

Precau­tions

Serious CNS disorders (seizure disorder)/ GI disorders
Renal impairment
Coumadin therapy
Children under 18
Pregnancy risk

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Cheatography n. The art of mapping complex subjects into clear, instantly navigable reference guides.