Urinary Tract Antiseptics
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Prototype Med
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Nitrofurantoin
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Other Meds
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Methenamine
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Acute UTIs
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Prophylaxis for recurrent lower UTIs
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Monitor/Report GI Symptoms (may reduce or change)
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Monitor/Report Respiratory Symptoms (may discontinue)
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Monitor/Report for Neuropathy
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Monitor lab values of blood components
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Monitor I&O and bowel function
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Take with food or milk
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Report dyspnea/fever/cough to provider
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Report numbness/tingling/weakness of extremities
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Report fatigue/bruising/repeated infections to provider
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Swallow liquid suspension
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Dilute liquid suspension
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Rinse mouth after taking suspension
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Concurrent use with antacids decrease absorption
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Probenecid increases the chance of toxicity
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Avoid drugs with potential for pulmonary toxicity
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Nausea/Vomiting/Diarrhea
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Acute: Chills/Fever/Cough (2-4 days)
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Subacute: Shortness of breath (weeks to months)
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Permanent peripheral neuropathy
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Anemia/Hemolytic Anemia/Thrombocytopenia/Neutropenia
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Tooth Staining (liquid suspension)
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Brown Urine (harmless)
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Dizziness/Drowsiness/Headache
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Photosensitivity
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Pulmonary Distress
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Oral Capsules (do not crush or chew)
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Macrodantin, Macrobid
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Liquid Suspension (dilute in milk or juice)
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Furadantin
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Allergy to nitrofurantoin
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Impaired kidney function
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History of jaundice caused by gallbladder disease
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Pregnancy at more than 38 weeks’ gestation
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During labor or delivery, lactating, infants -1 month
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Asthma, Liver/Kidney disease
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Electrolyte Imbalance
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Vitamin B12 deficiency
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