Progesterone is used as a contraceptive, protection for clients on HRT, endometriosis, Dysfunctional uterine bleeding, and palliative treatment for advanced uterine cancer.
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Prototype Med
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Medroxyprogesterone Acetate
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Provera
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Other Meds
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norethindrone (Micronor)
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Megestrol acetate (Megace)
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Treatment of endometriosis
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Treatment of dysfunctional uterine bleeding
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Treatment of endometrial carcinoma
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Thromboembolism/Breast cancer
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Breakthrough bleeding and other menstrual irregularities
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Nausea/Edema
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Monitor for and report any indications of deep vein thrombosis, pulmonary embolism, myocardial infarction, and cerebrovascular accident.
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Encourage clients who smoke to quit.
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Recommend mammograms and breast examinations at appropriate intervals.
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Discontinue the drug for any indications of breast cancer.
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Monitor the pattern and amount of any reported bleeding.
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Inform clients that this effect diminishes with time.
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Monitor weight.
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Give orally daily or cyclically or via IM injection.
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Expect amenorrhea and other menstrual irregularities.
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Report leg or chest pain, leg edema, sudden change in vision, severe head- ache, or shortness of breath.
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Do not smoke.
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Stop taking at least 4 weeks before any surgery that increases the risk of thromboembolic events.
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Perform breast self-examination every month.
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Obtain a mammogram and breast examination at the recommended intervals.
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Report any unusual breakthrough bleeding or spotting or changes in menstru- al patterns.
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Take oral forms with food. Take at bedtime.
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Pregnancy - teratogenic effects
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History of or high risk for thromboembolic events
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Undiagnosed vaginal bleeding
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Liver disease
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Cervical, uterine, vaginal, or breast cancer
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Asthma/Siezures/Migraines
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Cerebrovascular accident
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Cardiac or kidney dysfunction
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Rifampin (Rifadin), ritonavir (Norvir), phenobarbital (Luminal), carbamazepine (Tegretol), primidone (Mysoline), phenytoin (Dilantin), and St. John’s wort can reduce the effectiveness of progesterones.
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Progesterones may require adjustments in the dosage of hypoglycemic drugs.
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