TCA cycle3 Cheat Sheet

A Education › Biology cheat sheet in English by rhettbro

!!!!!!!!!!!!!!!!!!!!!!!!!!!

5,462 views 1,590 downloads 14 Apr 2021 History

Disruption of TCA cycle may cause health issue

Disruption of TCA cycle may cause health issue

phosph­atase deficiency

pyruvate dehydr­ogenase is always phosph­ory­lated and thus inactive.
Conseq­uently, glucose is processed to lactate rather than acetyl CoA.
This condition results in unremi­tting lactic acidos­is—high blood levels of lactic acid.
. In such an acidic enviro­nment, many tissues malfun­ction, most notably the central nervous system.
Nausea­,Vo­mit­ing­,Ab­dominal pain,A­nxi­ety...

Summary

Pyruvate Dehydr­ogenase Links Glycolysis to the Citric Acid Cycle
Oxidative decarb­oxy­lation, from pyruvate to acetyl CoA, Mt
The Citric Acid Cycle Oxidizes Two-Carbon Units
8 steps, 3 irreve­rsible steps, 3 NADH, 1 FADH2, 1 ATP, 2 CO2
Entry to the Citric Acid Cycle and Metabolism Through It Are Controlled
PDH, isocitrate dehydr­oge­nase, alpha-­Ket­ogl­utarate dehydr­ogenase
The Citric Acid Cycle Is a Source of Biosyn­thetic Precursors
Citrate, alpha-­ket­ogl­uta­rate, succinyl CoA, oxaloa­cetate

Comments

No comments yet.

Cheatography n. The art of mapping complex subjects into clear, instantly navigable reference guides.