|
Factor
|
Autonomic
|
Somatic
|
|
Effectors
|
Smooth muscle and glands
|
Skeletal Muscle
|
|
Efferent Pathways
|
Two neuron chain with ganglia
|
Single Neuron
|
|
NT Effects
|
PS: ACh / S: NE (can be inhibitory or stimulatory)
|
ACh (only stimulatory)
|
|
Factor
|
Parasympathetic
|
Sympathetic
|
|
Origin Site
|
Brain & Spinal Cord
|
Thoracolumbar
|
|
Pre/Post Fiber Length
|
Long/Short
|
Short/Long
|
|
Ganglia Location
|
In Visceral Effector Organs
|
Close to Spinal Cord
|
|
Type
|
Location
|
Effect on Binding
|
|
Nicotinic (ACh)
|
All Gang. Neurons; Adrenal Medullary Cells; NMJ
|
Ex.
|
|
Muscarinic (ACh)
|
All Para targets (symp. eccrine sweat glands and blood vessels in skel musc.)
|
Ex (xcept heart); Activation
|
|
B1 (NE/E)
|
HEART + kidneys + adipose tissue
|
HR/FORCE; RENIN
|
|
B2 (NE/E)
|
Lungs, Symp Tissue, BV (heart, liver, skel m.)
|
Mostly Inhibitory
|
|
B3 (NE/E)
|
Adipocytes
|
LIPOLYSIS
|
|
A1
|
BV in viscera, skin, mucosa; All Sym. targets except heart
|
BV CONSTRICT; pupils dilate
|
|
A2
|
Adrenergic axon term.; Pancreas; Platelets
|
Inh. NE + insulin release; Up Clotting
|
|
[III]
|
Constrict Pupils; Bulge Lenses
|
|
[VII]
|
Nasal + Lacrimal Glands -or- Sublingual + Submandibular
|
|
[IX]
|
Activate Parotid Salivary Glands
|
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